Parent Resources

Diphenhydramine (Benadryl, etc.) Dosage Table



Child's Weight (pounds) 20-24 25-37 38-49 50-99 100+ lbs
Liquid 12.5mg/5mL (tsp) ¾ 1 1½ 2 -- tsp
Chewable 12.5 mg -- 1 1½ 2 4 tablets
Capsules 25 mg -- -- -- 1 2 caps

Indications: Treatment of allergic reactions, nasal allergies, hives and itching.
Table Notes:

  • AGE LIMITS: For allergies, don't use under 1 year of age (Reason: it's a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).
  • DOSAGE: Determine by finding child's weight in the top row of the dosage table
  • FREQUENCY: Repeat every 6 hours as needed
  • ADULT DOSAGE: 50 mg
  • CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets
  • MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.

Disclaimer: This information is not intended to be a substitute for professional medical advice. It is provided for educational purposes only. You assume full responsibility for how you choose to use this information.

Source: American Academy of Pediatrics, Healthychildren.org

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